DNA Alkylator/Crosslinker,EGFR Antibody, Unconjugated Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB3031943-IH
Supplier Catalog Number:
orb3031943
Alternative Catalog Number:
BYT-ORB3031943-1, BYT-ORB3031943-5
Manufacturer:
Biorbyt
Category:
Antikörper
Conjugation:
Unconjugated
MHES0488A is a selective humanized antibody targeting HER2, with a KD value of 0.8 nM. It constitutes the antibody portion of DHES0815A. Upon cellular internalization, MHES0488A is transported to lysosomes, releasing PBD-monoamide into the nucleus, where it alkylates DNA, inducing DNA damage and apoptosis. It shows potential for research in cancers such as HER2-positive breast cancer and gastric cancer.
Target:
EGFR,DNA Alkylator/Crosslinker
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