EP2 receptor antagonist-3, CAS [[1799626-16-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: EP2 receptor antagonist-3, CAS [[1799626-16-6]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3136344
• Hersteller Artikelnummer: orb3136344
• Alternativnummer: BYT-ORB3136344-10, BYT-ORB3136344-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, with an IC50 of 8 nM determined in the hEP2 SPA assay and an IC50 of 50 nM in the hEP2 cAMP assay. It enhances macrophage-mediated clearance of Amyloid-beta plaques. In CD-1 mice, it shows moderate clearance and good exposure, and exhibits good central nervous system (CNS) exposure in both mice and rats. EP2 receptor antagonist-3 is applicable for research in Alzheimers disease.

Produkteigenschaften

• Molekulargewicht: 423.87
• CAS Nummer: [1799626-16-6]
• Formel: C23H19ClFN3O2
• Target-Kategorie: Beta Amyloid,Prostaglandin Receptor