EP2 receptor antagonist-3, CAS [[1799626-16-6]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB3136344
Supplier Catalog Number:
orb3136344
Alternative Catalog Number:
BYT-ORB3136344-10, BYT-ORB3136344-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
EP2 receptor antagonist-3 is a selective antagonist of the EP2 receptor, with an IC50 of 8 nM determined in the hEP2 SPA assay and an IC50 of 50 nM in the hEP2 cAMP assay. It enhances macrophage-mediated clearance of Amyloid-beta plaques. In CD-1 mice, it shows moderate clearance and good exposure, and exhibits good central nervous system (CNS) exposure in both mice and rats. EP2 receptor antagonist-3 is applicable for research in Alzheimers disease.
Molecular Weight:
423.87
CAS Number:
[1799626-16-6]
Formula:
C23H19ClFN3O2
Target:
Beta Amyloid,Prostaglandin Receptor
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