RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM, targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2.
Molekulargewicht:
449.983
Reinheit:
>98%
CAS Nummer:
[1579978-17-8]
Formel:
C25H28ClN5O
Chemical Structure: 1579978-17-8
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