RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM, targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2.
Molecular Weight:
449.983
Purity:
>98%
CAS Number:
[1579978-17-8]
Formula:
C25H28ClN5O
Chemical Structure: 1579978-17-8
* VAT and and shipping costs not included. Errors and price changes excepted