NFkappaB-p65 (Acetyl Lys218) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: NFkappaB-p65 (Acetyl Lys218) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1109
• Hersteller Artikelnummer: ES1109
• Alternativnummer: EBT-ES1109-50, EBT-ES1109-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human NFkappaB-p65 around the Acetylation site of Lys218. AA range:181-230
• Alternative Synonym: RELA, NFKB3, Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Produktbeschreibung

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 60kD
• NCBI: 5970
• UniProt: Q04206

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Bilder

Western Blot analysis of Jurkat, K562 cells using Acetyl-NFkappaB-p65 (K218) Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog:RS0002) was diluted at 1:20000

Western Blot analysis of MOUSE-BRAIN cells using Acetyl-NFkappaB-p65 (K218) Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100

The picture was kindly provided by our customer,antibody was diluted at 1:500