Syk (phospho Tyr348) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Syk (phospho Tyr348) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1480
• Hersteller Artikelnummer: ES1480
• Alternativnummer: EBT-ES1480-50, EBT-ES1480-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Monkey, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348. AA range:314-363
• Alternative Synonym: SYK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk

Produktbeschreibung

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 72kD
• NCBI: 6850
• UniProt: P43405

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using Phospho-Syk (Y348) Polyclonal Antibody

Western Blot analysis of 3T3 cells using Phospho-Syk (Y348) Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4 overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using SYK (Phospho-Tyr348) Antibody