Syk (phospho Tyr348) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Syk (phospho Tyr348) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1480
• Supplier Catalog Number: ES1480
• Alternative Catalog Number: EBT-ES1480-50, EBT-ES1480-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Monkey, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348. AA range:314-363
• Alternative Names: SYK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk

Product Description

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 72kD
• NCBI: 6850
• UniProt: P43405

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using Phospho-Syk (Y348) Polyclonal Antibody

Western Blot analysis of 3T3 cells using Phospho-Syk (Y348) Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4 overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using SYK (Phospho-Tyr348) Antibody