ACTR-IB rabbit pAb, Rabbit, Polyclonal

Artikelnummer: EBT-ES1597
Artikelname: ACTR-IB rabbit pAb, Rabbit, Polyclonal
Artikelnummer: EBT-ES1597
Hersteller Artikelnummer: ES1597
Alternativnummer: EBT-ES1597-50, EBT-ES1597-100
Hersteller: ELK Biotechnology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human ACV1B. AA range:73-122
Alternative Synonym: ACVR1B, ACVRLK4, ALK4, Activin receptor type-1B, Activin receptor type IB, ACTR-IB, Activin receptor-like kinase 4, ALK-4, Serine/threonine-protein kinase receptor R2, SKR2
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010],
Klonalität: Polyclonal
Konzentration: 1 mg/ml
Molekulargewicht: 56kD
NCBI: 91
UniProt: P36896
Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Western Blot analysis of various cells using ACTR-IB Polyclonal Antibody diluted at 1:1000
Immunofluorescence analysis of HeLa cells, using ACV1B Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from 293 and mouse liver cells, using ACV1B Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).