ACTR-IB rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: ACTR-IB rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1597
• Supplier Catalog Number: ES1597
• Alternative Catalog Number: EBT-ES1597-50, EBT-ES1597-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human ACV1B. AA range:73-122
• Alternative Names: ACVR1B, ACVRLK4, ALK4, Activin receptor type-1B, Activin receptor type IB, ACTR-IB, Activin receptor-like kinase 4, ALK-4, Serine/threonine-protein kinase receptor R2, SKR2

Product Description

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 56kD
• NCBI: 91
• UniProt: P36896

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using ACTR-IB Polyclonal Antibody diluted at 1:1000

Immunofluorescence analysis of HeLa cells, using ACV1B Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from 293 and mouse liver cells, using ACV1B Antibody. The lane on the right is blocked with the synthesized peptide.

Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).