BMP-3 rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: BMP-3 rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1776
• Hersteller Artikelnummer: ES1776
• Alternativnummer: EBT-ES1776-50, EBT-ES1776-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-3. AA range:257-306
• Alternative Synonym: BMP3, BMP3A, Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin

Produktbeschreibung

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 53kD
• NCBI: 651
• UniProt: P12645

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using BMP-3 Polyclonal Antibody diluted at 1:2000

Immunohistochemistry analysis of BMP-3 antibody in paraffin-embedded human lung carcinoma tissue.

Western blot analysis of lysate from HeLa cells, using BMP-3 antibody.