BMP-3 rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: BMP-3 rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1776
• Supplier Catalog Number: ES1776
• Alternative Catalog Number: EBT-ES1776-50, EBT-ES1776-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human BMP-3. AA range:257-306
• Alternative Names: BMP3, BMP3A, Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin

Product Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 53kD
• NCBI: 651
• UniProt: P12645

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using BMP-3 Polyclonal Antibody diluted at 1:2000

Immunohistochemistry analysis of BMP-3 antibody in paraffin-embedded human lung carcinoma tissue.

Western blot analysis of lysate from HeLa cells, using BMP-3 antibody.