ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES20012
• Hersteller Artikelnummer: ES20012
• Alternativnummer: EBT-ES20012-50, EBT-ES20012-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human ITGA2B (light chain form 1, Cleaved-Gln891)
• Alternative Synonym: Integrin alpha-IIb (GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb,CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2]

Produktbeschreibung

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 16 110kD
• NCBI: 3674
• UniProt: P08514

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-2000,IHC-p 1:50-300

Bilder

Immunohistochemical analysis of paraffin-embedded human spleen. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).