ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number:
EBT-ES20012
Supplier Catalog Number:
ES20012
Alternative Catalog Number:
EBT-ES20012-50, EBT-ES20012-100
Manufacturer:
ELK Biotechnology
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from human ITGA2B (light chain form 1, Cleaved-Gln891)
Alternative Names:
Integrin alpha-IIb (GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb,CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2]
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
Immunohistochemical analysis of paraffin-embedded human spleen. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
* VAT and and shipping costs not included. Errors and price changes excepted
