Fascin 1 rabbit pAb, Rabbit, Polyclonal

Artikelnummer: EBT-ES3942
Artikelname: Fascin 1 rabbit pAb, Rabbit, Polyclonal
Artikelnummer: EBT-ES3942
Hersteller Artikelnummer: ES3942
Alternativnummer: EBT-ES3942-50, EBT-ES3942-100
Hersteller: ELK Biotechnology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FSCN1. AA range:261-310
Alternative Synonym: FSCN1, FAN1, HSN, SNL, Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkins lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],
Klonalität: Polyclonal
Konzentration: 1 mg/ml
Molekulargewicht: 55kD
NCBI: 6624
UniProt: Q16658
Application Verdünnung: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.