Fascin 1 rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES3942
Article Name: Fascin 1 rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number: EBT-ES3942
Supplier Catalog Number: ES3942
Alternative Catalog Number: EBT-ES3942-50, EBT-ES3942-100
Manufacturer: ELK Biotechnology
Host: Rabbit
Category: Antikörper
Application: ELISA, IF, IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FSCN1. AA range:261-310
Alternative Names: FSCN1, FAN1, HSN, SNL, Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkins lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],
Clonality: Polyclonal
Concentration: 1 mg/ml
Molecular Weight: 55kD
NCBI: 6624
UniProt: Q16658
Application Dilute: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.