Mi2-beta rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Mi2-beta rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES4590
• Hersteller Artikelnummer: ES4590
• Alternativnummer: EBT-ES4590-50, EBT-ES4590-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC
• Spezies Reaktivität: Human, Mouse
• Immunogen: The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620
• Alternative Synonym: CHD4, Chromodomain-helicase-DNA-binding protein 4, CHD-4, ATP-dependent helicase CHD4, Mi-2 autoantigen 218 kDa protein, Mi2-beta

Produktbeschreibung

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• NCBI: 1108
• UniProt: Q14839

Anwendungsbeschreibung

• Application Verdünnung: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Bilder

Immunofluorescence analysis of HepG2 cells, using CHD4 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using CHD4 Antibody. The picture on the right is blocked with the synthesized peptide.