Mi2-beta rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Mi2-beta rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES4590
• Supplier Catalog Number: ES4590
• Alternative Catalog Number: EBT-ES4590-50, EBT-ES4590-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC
• Species Reactivity: Human, Mouse
• Immunogen: The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620
• Alternative Names: CHD4, Chromodomain-helicase-DNA-binding protein 4, CHD-4, ATP-dependent helicase CHD4, Mi-2 autoantigen 218 kDa protein, Mi2-beta

Product Description

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• NCBI: 1108
• UniProt: Q14839

Application Notes

• Application Dilute: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Images

Immunofluorescence analysis of HepG2 cells, using CHD4 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using CHD4 Antibody. The picture on the right is blocked with the synthesized peptide.