4-O10b1

Produktübersicht

• Artikelname: 4-O10b1
• Artikelnummer: ECH-N-1114
• Hersteller Artikelnummer: N-1114
• Alternativnummer: ECH-N-1114-10MG, ECH-N-1114-25MG, ECH-N-1114-50MG, ECH-N-1114-5MG
• Hersteller: Echelon Biosciences
• Kategorie: Molekularbiologie

Produktbeschreibung

4-O10b1 is an ionizable lipid used to generate lipid nanoparticles (LNPs) for delivering RNA to cells. LNPs comprised of 4-O10b1 and conjugated with the macrophage antibody F4/80 were able to delivery siRNA targeting TAK1 to RAW264.7 cells resulting in suppressed activation of NF-kB. Intranasal administration reduced lung injury in an influenza mouse model.