4-O10b1

Product Overview

• Article Name: 4-O10b1
• Biozol Catalog Number: ECH-N-1114
• Supplier Catalog Number: N-1114
• Alternative Catalog Number: ECH-N-1114-10MG, ECH-N-1114-25MG, ECH-N-1114-50MG, ECH-N-1114-5MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

4-O10b1 is an ionizable lipid used to generate lipid nanoparticles (LNPs) for delivering RNA to cells. LNPs comprised of 4-O10b1 and conjugated with the macrophage antibody F4/80 were able to delivery siRNA targeting TAK1 to RAW264.7 cells resulting in suppressed activation of NF-kB. Intranasal administration reduced lung injury in an influenza mouse model.