Integrin beta 3 (3C12) Mouse Monoclonal Antibody, IgG1, Unconjugated

Produktübersicht

• Artikelname: Integrin beta 3 (3C12) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Artikelnummer: EKL-AMM03440
• Hersteller Artikelnummer: AMM03440
• Alternativnummer: EKL-AMM03440-50UL,EKL-AMM03440-100UL,EKL-AMM03440-500UL,EKL-AMM03440-200UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: ITGB3, GP3A, Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD antigen CD61

Produktbeschreibung

Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 87 kDa, Observed MW: 110 kDa
• Isotyp: IgG1
• NCBI: 3690
• UniProt: P05106
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: ITGB3

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500-1:1000