Integrin beta 3 (3C12) Mouse Monoclonal Antibody, IgG1, Unconjugated

Product Overview

• Article Name: Integrin beta 3 (3C12) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Biozol Catalog Number: EKL-AMM03440
• Supplier Catalog Number: AMM03440
• Alternative Catalog Number: EKL-AMM03440-50UL, EKL-AMM03440-100UL, EKL-AMM03440-200UL
• Manufacturer: EnkiLife
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: ITGB3, GP3A, Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD antigen CD61

Product Description

Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: Calculated MW: 87 kDa, Observed MW: 110 kDa
• Isotype: IgG1
• NCBI: 3690
• UniProt: P05106
• Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Purity: Affinity Purification
• Form: Liquid
• Target: ITGB3

Application Notes

• Application Dilute: WB 1:500-1:1000