CRK (3H7) Mouse Monoclonal Antibody, IgG2b, Unconjugated

Produktübersicht

• Artikelname: CRK (3H7) Mouse Monoclonal Antibody, IgG2b, Unconjugated
• Artikelnummer: EKL-AMM03483
• Hersteller Artikelnummer: AMM03483
• Alternativnummer: EKL-AMM03483-50UL,EKL-AMM03483-100UL,EKL-AMM03483-500UL,EKL-AMM03483-200UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: Adapter molecule crk, avian sarcoma virus CT10 (v-crk) oncogene homolog, CRK, CRKII, Proto-oncogene c-Crk

Produktbeschreibung

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 34 kDa, Observed MW: 34 kDa
• Isotyp: IgG2b
• NCBI: 1398
• UniProt: P46108
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: CRK

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500-1:1000