CRK (3H7) Mouse Monoclonal Antibody, IgG2b, Unconjugated

Product Overview

• Article Name: CRK (3H7) Mouse Monoclonal Antibody, IgG2b, Unconjugated
• Biozol Catalog Number: EKL-AMM03483
• Supplier Catalog Number: AMM03483
• Alternative Catalog Number: EKL-AMM03483-50UL,EKL-AMM03483-100UL,EKL-AMM03483-500UL,EKL-AMM03483-200UL
• Manufacturer: EnkiLife
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: Adapter molecule crk, avian sarcoma virus CT10 (v-crk) oncogene homolog, CRK, CRKII, Proto-oncogene c-Crk

Product Description

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: Calculated MW: 34 kDa, Observed MW: 34 kDa
• Isotype: IgG2b
• NCBI: 1398
• UniProt: P46108
• Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Purity: Affinity Purification
• Form: Liquid
• Target: CRK

Application Notes

• Application Dilute: WB: 1:500-1:1000