MCL-1 Mouse Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: MCL-1 Mouse Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMM80516
• Hersteller Artikelnummer: AMM80516
• Alternativnummer: EKL-AMM80516-50UL,EKL-AMM80516-100UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, ICC, IHC, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: EAT, MCL1L, MCL1S

Produktbeschreibung

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that
increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or
exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related
protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This
monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 37kDa
• NCBI: 4170
• UniProt: Q07820
• Puffer: Purified antibody in PBS with 0.05% sodium azide
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: MCL-1

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000