MCL-1 Mouse Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: MCL-1 Mouse Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMM80516
• Supplier Catalog Number: AMM80516
• Alternative Catalog Number: EKL-AMM80516-50UL,EKL-AMM80516-100UL
• Manufacturer: EnkiLife
• Host: Mouse
• Category: Antikörper
• Application: ELISA, ICC, IHC, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: EAT, MCL1L, MCL1S

Product Description

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that
increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or
exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related
protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This
monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 37kDa
• NCBI: 4170
• UniProt: Q07820
• Buffer: Purified antibody in PBS with 0.05% sodium azide
• Purity: Affinity Purification
• Form: Liquid
• Target: MCL-1

Application Notes

• Application Dilute: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000