PRAS40 Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: PRAS40 Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE03162
• Hersteller Artikelnummer: AMRe03162
• Alternativnummer: EKL-AMRE03162-50UL, EKL-AMRE03162-100UL, EKL-AMRE03162-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IP, WB
• Spezies Reaktivität: Human, Rat
• Konjugation: Unconjugated
• Alternative Synonym: AKT1S1, PRAS40, Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate

Produktbeschreibung

PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 27 kDa, Observed MW: 40 kDa
• NCBI: 84335
• UniProt: Q96B36
• Puffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: AKT1S1

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:1000,IP 1:20-1:50