PRAS40 Rabbit Monoclonal Antibody, Unconjugated
Catalog Number:
EKL-AMRE03162
Product Overview
Article Name:
PRAS40 Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE03162
Supplier Catalog Number:
AMRe03162
Alternative Catalog Number:
EKL-AMRE03162-50UL, EKL-AMRE03162-100UL, EKL-AMRE03162-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
IP, WB
Species Reactivity:
Human, Rat
Conjugation:
Unconjugated
Alternative Names:
AKT1S1, PRAS40, Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate
Product Description
PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
Product Properties
Clonality:
Monoclonal
Molecular Weight:
Calculated MW: 27 kDa, Observed MW: 40 kDa
NCBI:
84335
UniProt:
Q96B36
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purity:
Affinity Purification
Form:
Liquid
Target:
AKT1S1
Application Notes
Application Dilute:
WB 1:500-1:1000,IP 1:20-1:50
