Furin (6Z15) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE11184
Artikelname: Furin (6Z15) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE11184
Hersteller Artikelnummer: AMRe11184
Alternativnummer: EKL-AMRE11184-50UL, EKL-AMRE11184-100UL, EKL-AMRE11184-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ICC, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: FUR, FURIN, PACE, PCSK3, SPC1,
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif (PubMed:11799113, PubMed:1629222, PubMed:1713771, PubMed:2251280, PubMed:24666235, PubMed:25974265, PubMed:7592877, PubMed:7690548, PubMed:9130696). Mediates processing of TGFB1, an essential step in TGF-beta-1 activation (PubMed:7737999). Converts through proteolytic cleavage the non-functional Brain natriuretic factor prohormone into its active hormone BNP(1-32) (PubMed:20489134, PubMed:21763278).
Klonalität: Monoclonal
Molekulargewicht: 87kDa
NCBI: 5045
UniProt: P09958
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: FURIN
Application Verdünnung: WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200