Furin (6Z15) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: Furin (6Z15) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE11184
• Supplier Catalog Number: AMRe11184
• Alternative Catalog Number: EKL-AMRE11184-50UL, EKL-AMRE11184-100UL, EKL-AMRE11184-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: FUR, FURIN, PACE, PCSK3, SPC1,

Product Description

Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif (PubMed:11799113, PubMed:1629222, PubMed:1713771, PubMed:2251280, PubMed:24666235, PubMed:25974265, PubMed:7592877, PubMed:7690548, PubMed:9130696). Mediates processing of TGFB1, an essential step in TGF-beta-1 activation (PubMed:7737999). Converts through proteolytic cleavage the non-functional Brain natriuretic factor prohormone into its active hormone BNP(1-32) (PubMed:20489134, PubMed:21763278).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 87kDa
• NCBI: 5045
• UniProt: P09958
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: FURIN

Application Notes

• Application Dilute: WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200