Galectin 8 (14S17) Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Galectin 8 (14S17) Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE11270
• Hersteller Artikelnummer: AMRe11270
• Alternativnummer: EKL-AMRE11270-50UL, EKL-AMRE11270-100UL, EKL-AMRE11270-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC, IP, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: LGALS8, Galectin-8g, Galectin-8, Po66-CBP, PCTA-1, Gal-8, Galectin 8, PCTA1,

Produktbeschreibung

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3-O-sialylated and 3-O-sulfated glycans (PubMed:21288902).

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 36kDa
• NCBI: 3964
• UniProt: O00214
• Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Reinheit: Affinity purification
• Formulierung: Liquid
• Target-Kategorie: LGALS8

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:50-1:100,FC 1:10-1:100,IP 1:10-1:100