Galectin 8 (14S17) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: Galectin 8 (14S17) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE11270
• Supplier Catalog Number: AMRe11270
• Alternative Catalog Number: EKL-AMRE11270-50UL, EKL-AMRE11270-100UL, EKL-AMRE11270-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IHC, IP, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: LGALS8, Galectin-8g, Galectin-8, Po66-CBP, PCTA-1, Gal-8, Galectin 8, PCTA1,

Product Description

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3-O-sialylated and 3-O-sulfated glycans (PubMed:21288902).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 36kDa
• NCBI: 3964
• UniProt: O00214
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: LGALS8

Application Notes

• Application Dilute: WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:50-1:100,FC 1:10-1:100,IP 1:10-1:100