MRP1 (7D13) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE14099
Produktübersicht
Artikelname:
MRP1 (7D13) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE14099
Hersteller Artikelnummer:
AMRe14099
Alternativnummer:
EKL-AMRE14099-50UL, EKL-AMRE14099-100UL, EKL-AMRE14099-200UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ICC, IHC, WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
ABC29, Abcc1, GSX, Leukotriene C(4) transporter, LTC4 transporter, MRP1,
Produktbeschreibung
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17- beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed: 7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed: 9281595). Hydrolyzes ATP with low efficiency (PubMed: 16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed: 17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).
Produkteigenschaften
Klonalität:
Monoclonal
Molekulargewicht:
172kDa
NCBI:
4363
UniProt:
P33527
Puffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit:
Affinity purification
Formulierung:
Liquid
Target-Kategorie:
ABCC1
Anwendungsbeschreibung
Application Verdünnung:
WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:20-1:100
