MRP1 (7D13) Rabbit Monoclonal Antibody, Unconjugated
Catalog Number:
EKL-AMRE14099
Product Overview
Article Name:
MRP1 (7D13) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE14099
Supplier Catalog Number:
AMRe14099
Alternative Catalog Number:
EKL-AMRE14099-50UL, EKL-AMRE14099-100UL, EKL-AMRE14099-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
ICC, IHC, WB
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
ABC29, Abcc1, GSX, Leukotriene C(4) transporter, LTC4 transporter, MRP1,
Product Description
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17- beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed: 7961706, PubMed: 16230346, PubMed: 9281595, PubMed: 10064732, PubMed: 11114332). Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed: 9281595). Hydrolyzes ATP with low efficiency (PubMed: 16230346). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed: 17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).
Product Properties
Clonality:
Monoclonal
Molecular Weight:
172kDa
NCBI:
4363
UniProt:
P33527
Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity:
Affinity purification
Form:
Liquid
Target:
ABCC1
Application Notes
Application Dilute:
WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:20-1:100
