PI 3 Kinase Class 3 (11Y1) Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: PI 3 Kinase Class 3 (11Y1) Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE16090
• Hersteller Artikelnummer: AMRe16090
• Alternativnummer: EKL-AMRE16090-50UL, EKL-AMRE16090-100UL, EKL-AMRE16090-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: PI3-kinase type 3, PI3K type 3, PI3 kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34, PIK3C3, Vps 34, Vps34

Produktbeschreibung

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. As part of PI3KC3-C1, promotes endoplasmic reticulum membrane curvature formation prior to vesicle budding (PubMed:32690950). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 102kDa
• NCBI: 5289
• UniProt: Q8NEB9
• Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Reinheit: Affinity purification
• Formulierung: Liquid
• Target-Kategorie: PIK3C3

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000-1:5000,IHC 1:50-1:100,IF-P 1:50-1:100