PI 3 Kinase Class 3 (11Y1) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: PI 3 Kinase Class 3 (11Y1) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE16090
• Supplier Catalog Number: AMRe16090
• Alternative Catalog Number: EKL-AMRE16090-50UL, EKL-AMRE16090-100UL, EKL-AMRE16090-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: PI3-kinase type 3, PI3K type 3, PI3 kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34, PIK3C3, Vps 34, Vps34

Product Description

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. As part of PI3KC3-C1, promotes endoplasmic reticulum membrane curvature formation prior to vesicle budding (PubMed:32690950). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 102kDa
• NCBI: 5289
• UniProt: Q8NEB9
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: PIK3C3

Application Notes

• Application Dilute: WB 1:1000-1:5000,IHC 1:50-1:100,IF-P 1:50-1:100