PHF8 Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: PHF8 Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE84004
• Hersteller Artikelnummer: AMRe84004
• Alternativnummer: EKL-AMRE84004-50UL,EKL-AMRE84004-100UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: Histone lysine demethylase PHF8, MRXSSD, PHD finger protein 8, PHF8, ZNF422,,PHF8

Produktbeschreibung

Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 Lys-9 residue (H3K9Me1 and H3K9Me2), dimethylated H3 Lys-27 (H3K27Me2) and monomethylated histone H4 Lys-20 residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 118 kDa , Observed MW: 140 kDa
• UniProt: Q9UPP1
• Puffer: Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: PHF8

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50