PHF8 Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: PHF8 Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE84004
• Supplier Catalog Number: AMRe84004
• Alternative Catalog Number: EKL-AMRE84004-50UL,EKL-AMRE84004-100UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: Histone lysine demethylase PHF8, MRXSSD, PHD finger protein 8, PHF8, ZNF422,,PHF8

Product Description

Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 Lys-9 residue (H3K9Me1 and H3K9Me2), dimethylated H3 Lys-27 (H3K27Me2) and monomethylated histone H4 Lys-20 residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: Calculated MW: 118 kDa , Observed MW: 140 kDa
• UniProt: Q9UPP1
• Buffer: Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
• Purity: Affinity Purification
• Form: Liquid
• Target: PHF8

Application Notes

• Application Dilute: WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50