Securin Rabbit Polyclonal Antibody, Unconjugated
Artikelnummer:
EKL-APRAB00269
Produktübersicht
Artikelname:
Securin Rabbit Polyclonal Antibody, Unconjugated
Artikelnummer:
EKL-APRAB00269
Hersteller Artikelnummer:
APRab00269
Alternativnummer:
EKL-APRAB00269-50UL,EKL-APRAB00269-100UL,EKL-APRAB00269-500UL,EKL-APRAB00269-20UL,EKL-APRAB00269-200UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, ICC, IHC-P, IP, WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
PTTG1, EAP1, PTTG, TUTR1, Securin, Esp1-associated protein, Pituitary tumor-transforming gene 1 protein, Tumor-transforming protein 1, hPTTG
Produktbeschreibung
Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
Produkteigenschaften
Klonalität:
Polyclonal
Molekulargewicht:
Calculated MW: 22 kDa, Observed MW: 28 kDa
NCBI:
9232
UniProt:
O95997
Puffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reinheit:
Affinity Chromatography
Formulierung:
Liquid
Target-Kategorie:
PTTG1
Anwendungsbeschreibung
Application Verdünnung:
WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100
