Securin Rabbit Polyclonal Antibody, Unconjugated

Product Overview

• Article Name: Securin Rabbit Polyclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-APRAB00269
• Supplier Catalog Number: APRab00269
• Alternative Catalog Number: EKL-APRAB00269-50UL,EKL-APRAB00269-100UL,EKL-APRAB00269-500UL,EKL-APRAB00269-20UL,EKL-APRAB00269-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IHC-P, IP, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: PTTG1, EAP1, PTTG, TUTR1, Securin, Esp1-associated protein, Pituitary tumor-transforming gene 1 protein, Tumor-transforming protein 1, hPTTG

Product Description

Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: Calculated MW: 22 kDa, Observed MW: 28 kDa
• NCBI: 9232
• UniProt: O95997
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purity: Affinity Chromatography
• Form: Liquid
• Target: PTTG1

Application Notes

• Application Dilute: WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100