Integrin beta 4 Rabbit Polyclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Integrin beta 4 Rabbit Polyclonal Antibody, Unconjugated
• Artikelnummer: EKL-APRAB00352
• Hersteller Artikelnummer: APRab00352
• Alternativnummer: EKL-APRAB00352-20UL, EKL-APRAB00352-50UL, EKL-APRAB00352-100UL, EKL-APRAB00352-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: CD104

Produktbeschreibung

Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: Calculated MW: 202 kDa, Observed MW: 202 kDa
• NCBI: 192897
• UniProt: A2A863
• Puffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: Itgb4

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:1000,IHC 1:50-1:100