Integrin beta 4 Rabbit Polyclonal Antibody, Unconjugated

Product Overview

• Article Name: Integrin beta 4 Rabbit Polyclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-APRAB00352
• Supplier Catalog Number: APRab00352
• Alternative Catalog Number: EKL-APRAB00352-20UL, EKL-APRAB00352-50UL, EKL-APRAB00352-100UL, EKL-APRAB00352-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: CD104

Product Description

Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: Calculated MW: 202 kDa, Observed MW: 202 kDa
• NCBI: 192897
• UniProt: A2A863
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Purity: Affinity Purification
• Form: Liquid
• Target: Itgb4

Application Notes

• Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100