Phospho-IRE1 (Ser724) Rabbit Polyclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Phospho-IRE1 (Ser724) Rabbit Polyclonal Antibody, Unconjugated
• Artikelnummer: EKL-APRAB00695
• Hersteller Artikelnummer: APRab00695
• Alternativnummer: EKL-APRAB00695-20UL, EKL-APRAB00695-50UL, EKL-APRAB00695-100UL, EKL-APRAB00695-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a

Produktbeschreibung

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: Calculated MW: 110 kDa, Observed MW: 110 kDa
• NCBI: 2081
• UniProt: O75460
• Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Reinheit: Affinity Chromatography
• Formulierung: Liquid
• Target-Kategorie: ERN1

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:1000