Phospho-IRE1 (Ser724) Rabbit Polyclonal Antibody, Unconjugated

Product Overview

• Article Name: Phospho-IRE1 (Ser724) Rabbit Polyclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-APRAB00695
• Supplier Catalog Number: APRab00695
• Alternative Catalog Number: EKL-APRAB00695-20UL, EKL-APRAB00695-50UL, EKL-APRAB00695-100UL, EKL-APRAB00695-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a

Product Description

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: Calculated MW: 110 kDa, Observed MW: 110 kDa
• NCBI: 2081
• UniProt: O75460
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purity: Affinity Chromatography
• Form: Liquid
• Target: ERN1

Application Notes

• Application Dilute: WB 1:500-1:1000