Sin3B Rabbit Polyclonal Antibody, Unconjugated

Artikelnummer: EKL-APRAB17904
Artikelname: Sin3B Rabbit Polyclonal Antibody, Unconjugated
Artikelnummer: EKL-APRAB17904
Hersteller Artikelnummer: APRab17904
Alternativnummer: EKL-APRAB17904-20UL, EKL-APRAB17904-50UL, EKL-APRAB17904-100UL, EKL-APRAB17904-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: SIN3B, KIAA0700, Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b
function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.,similarity:Contains 3 PAH (paired amphipathic helix) repeats.,subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.,similarity:Contains 3 PAH (paired amphipathic helix) repeats.,subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,
Klonalität: Polyclonal
Molekulargewicht: 130kDa
NCBI: 23309
UniProt: O75182
Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: SIN3B
Application Verdünnung: WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000