Sin3B Rabbit Polyclonal Antibody, Unconjugated

Catalog Number: EKL-APRAB17904
Article Name: Sin3B Rabbit Polyclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-APRAB17904
Supplier Catalog Number: APRab17904
Alternative Catalog Number: EKL-APRAB17904-20UL, EKL-APRAB17904-50UL, EKL-APRAB17904-100UL, EKL-APRAB17904-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC, WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: SIN3B, KIAA0700, Paired amphipathic helix protein Sin3b, Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b
function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.,similarity:Contains 3 PAH (paired amphipathic helix) repeats.,subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.,similarity:Contains 3 PAH (paired amphipathic helix) repeats.,subunit:Interacts with FOXK1/MNF, MXI, MAD, NCOR1 and SAP30. Interaction with SDS3 enhances the interaction with HDAC1 to form a complex. Interacts with MAD3, MAD4, MAEL, REST and SETDB1 (By similarity). Interacts with HCFC1.,
Clonality: Polyclonal
Molecular Weight: 130kDa
NCBI: 23309
UniProt: O75182
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Purity: Affinity purification
Form: Liquid
Target: SIN3B
Application Dilute: WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000