SP-A Rabbit Polyclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: SP-A Rabbit Polyclonal Antibody, Unconjugated
• Artikelnummer: EKL-APRAB18156
• Hersteller Artikelnummer: APRab18156
• Alternativnummer: EKL-APRAB18156-20UL, EKL-APRAB18156-50UL, EKL-APRAB18156-100UL, EKL-APRAB18156-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, ICC, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B, Pulmonary surfactant-associated protein A2, PSP-A, PSPA, SP-A, SP-A2, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5, SFTPA1, COLEC4, PSAP,SFTP1, SFTPA, SFTPA1B, Pulmonary surfactant-associated protein A1, PSP-A, PSPA, SP-A, SP-A1, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-4

Produktbeschreibung

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009],function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.,miscellaneous:Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).,polymorphism:At least 6 alleles of SFTPA2 are known: 1A, 1A(0), 1A(1), 1A(2), 1A(3) and 1A(4). The sequence shown is that of allele 1A(0).,similarity:Belongs to the SFTPA family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 collagen-like domain.,subunit:Oligomeric complex of 6 set of homotrimers.,

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 34kDa
• NCBI: 729238
• UniProt: Q8IWL1
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
• Reinheit: Affinity purification
• Formulierung: Liquid
• Target-Kategorie: SFTPA2/SFTPA1

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000