SP-A Rabbit Polyclonal Antibody, Unconjugated
Catalog Number:
EKL-APRAB18156
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| Article Name: | SP-A Rabbit Polyclonal Antibody, Unconjugated |
| Biozol Catalog Number: | EKL-APRAB18156 |
| Supplier Catalog Number: | APRab18156 |
| Alternative Catalog Number: | EKL-APRAB18156-20UL, EKL-APRAB18156-50UL, EKL-APRAB18156-100UL, EKL-APRAB18156-200UL |
| Manufacturer: | EnkiLife |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Conjugation: | Unconjugated |
| Alternative Names: | SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B, Pulmonary surfactant-associated protein A2, PSP-A, PSPA, SP-A, SP-A2, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5, SFTPA1, COLEC4, PSAP,SFTP1, SFTPA, SFTPA1B, Pulmonary surfactant-associated protein A1, PSP-A, PSPA, SP-A, SP-A1, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-4 |
| This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009],function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.,miscellaneous:Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).,polymorphism:At least 6 alleles of SFTPA2 are known: 1A, 1A(0), 1A(1), 1A(2), 1A(3) and 1A(4). The sequence shown is that of allele 1A(0).,similarity:Belongs to the SFTPA family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 collagen-like domain.,subunit:Oligomeric complex of 6 set of homotrimers., |
| Application Dilute: | WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000 |
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