Recombinant Human PDCD4 (C-6His), E. coli

Produktübersicht

• Artikelname: Recombinant Human PDCD4 (C-6His), E. coli
• Artikelnummer: EKL-PEH1280
• Hersteller Artikelnummer: PEH1280
• Alternativnummer: EKL-PEH1280-10UG,EKL-PEH1280-50UG,EKL-PEH1280-500UG
• Hersteller: EnkiLife
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Alternative Synonym: Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731

Produktbeschreibung

Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.

Produkteigenschaften

• Molekulargewicht: 17 KDa
• NCBI: 53
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.