Recombinant Human PDCD4 (C-6His), E. coli

Product Overview

• Article Name: Recombinant Human PDCD4 (C-6His), E. coli
• Biozol Catalog Number: EKL-PEH1280
• Supplier Catalog Number: PEH1280
• Alternative Catalog Number: EKL-PEH1280-10UG,EKL-PEH1280-50UG,EKL-PEH1280-500UG
• Manufacturer: EnkiLife
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731

Product Description

Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.

Product Properties

• Molecular Weight: 17 KDa
• NCBI: 53
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.